A war with Israel and Iran is inevitable.
Thomas P.M. Barnett sees a war against Iran as inevitable:
While the debate over whether Israel will strike Iran ebbs and flows on an almost weekly basis now, a larger collision-course trajectory is undeniably emerging. To put it most succinctly, Iran won't back down, while Israel won't back off, and America will back up its two regional allies -- Israel and Saudi Arabia -- when the shooting finally starts. There are no other credible paths in sight: There will be no diplomatic miracles, and Iran will not be permitted to achieve a genuine nuclear deterrence. But let us also be clear about what this coming war will ultimately target: regime change in Tehran, because that is the only plausible solution.
While I don't know if Israel and the U.S. will reach as far as an attempted regime change, I think Israeli air strikes are almost certainly coming.